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The New England Journal of Medicine
In a high-risk population, vaccination was better than prior infection, with incremental increase in protection with additional vaccination doses. Prior infection in unvaccinated individuals ranged from 16% to 49% vs omicron infection Versus unvaccinated, previously uninfected individuals, vaccine effectiveness at preventing omicron infection ranged from 19% to 83% with 2 doses and 41% to 88% with 3 doses Three vaccine doses offered significantly more protection than two doses, including among previously infected persons
Allergy & Immunology November 14th 2022
MedPage Today
Aniruddha Hazra, MD, of Howard Brown Health in Chicago, and colleagues found that of 90 people who tested positive for monkeypox following a single dose of Jynneos, 77% of the cases happened within 14 days of the first dose and 14% occurred within 14-28 days of the first dose. Five positive tests were returned following a second dose of the modified vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine in the eight cases that occurred 28 days after vaccine initiation.
Allergy & Immunology November 9th 2022
In the US, reports of COVID-related clots have declined. But social media posts in the UK indicate a rise there – and typically what the UK reports is a harbinger of what is coming to the US.
A 5-year-old boy from China who had IgA vasculitis at age 2 presented with progressively painful skin ulcerations on his extremities for the past month. Find the reason behind the skin lesions on this young boy by answering the image challenge.
JAMA Network
The median time to recovery in a group of 1,800 vaccinated and unvaccinated adults (median age: 48 years) was essentially the same whether the patients received ivermectin or placebo: 12 and 13 days, respectively. Death rate was slightly higher in the ivermectin group and rates of pneumonia and VTE were slightly higher in the placebo group.
Allergy & Immunology November 2nd 2022
In this cross-sectional study of US adults hospitalized with COVID-19 during January 2022 to April 2022, hospitalization rates from COVID were 10.5 times higher in unvaccinated persons and 2.5 times higher in vaccinated persons with no booster dose, respectively, compared with those who had received a booster dose.
Allergy & Immunology September 20th 2022