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Journal of Clinical Oncology
Both immune checkpoint inhibitors (ICIs) and VEGF receptor inhibitors are approved for advanced renal cell carcinoma (RCC) treatment and can cause cardiovascular events (CVs). This randomized study of avelumab plus axitinib vs. sunitinib used prospective monitoring of LVEF and serum cardiac biomarkers to assess for the development of major adverse CV events. The results indicate patients with high baseline troponin T levels and who receive combination ICI and VEGF receptor inhibitor therapy should be monitored closely for adverse cardiac events.
Cardiology March 15th 2022
ACP Internist
Can you determine the appropriate case management for a 68-year-old man who is evaluated for an episode of syncope and repeated episodes of near-fainting when standing and working on his tractor? On physical examination, vital signs are normal. Supine blood pressure is 124/78 mm Hg, and pulse rate is 76/min. After the patient stands for three minutes, standing blood pressure is 88/68 mm Hg, and pulse rate is 94/min. The remainder of the examination is normal. How would you proceed?
Cardiology February 15th 2022
JAMA Network
A new cohort study has found physical, mental, and cognitive symptoms in patients one year after being treated in an intensive care unit (ICU) for COVID-19. The study involved an exploratory multicenter prospective cohort study that included 246 patients who were alive one year following ICU treatment for COVID-19. Three-quarters of patients reported physical symptoms, 1/4 reported mental symptoms, and about 15% reported cognitive symptoms a year after being hospitalized with the respiratory illness.
Cardiology February 8th 2022
American Thoracic Society
A proposed six-step approach to making sense of arterial blood gas (ABG) labs. This six-step process with simple table support helps ensure a complete and understandable interpretation of every ABG.
Cleveland Clinic Journal of Medicine (CCJM)
A study published in the Cleveland Clinic Journal of Medicine puts forward a new and systematic approach to diagnosing and managing orthostatic hypotension. The article notes that current approaches to evaluating and managing the disease are based on limited data, but that patients would benefit from more consistent diagnosis and treatment methods.
Cardiology January 25th 2022
Thinking of starting the new year off with a diet? According to U.S. News and World Report, the Mediterranean diet is the best overall diet for adults. The diet was ranked first in the categories of best diets for healthy eating, easiest diets to follow, and best diets for diabetes, among other measurable categories.
Allergy & Immunology January 19th 2022