Articles related to Cardiology

Whole-genome sequencing of nearly one million participants identified pathogenic DMPK repeat expansions more frequently than historical estimates of myotonic dystrophy type 1 prevalence, while linking expansion status with cardiac conduction disorders and early-onset cataracts.

The American Heart Association has updated infective endocarditis guidance to incorporate the 2023 Duke/ISCVID diagnostic criteria, advanced microbiologic diagnostics, contemporary imaging recommendations, and evolving antimicrobial treatment approaches while emphasizing multidisciplinary management.

A single-case report describes SAFE-SEAL, a percutaneous bailout technique that restored hemostasis after failure of hybrid femoral closure during transfemoral TAVR, suggesting a potential alternative to more invasive rescue strategies when guidewire access has been lost.

In a prospective cohort of more than 112,000 French adults, higher intake of several commonly used food preservatives was associated with increased risks of hypertension and cardiovascular disease, though the observational design cannot determine whether the additives themselves caused the observed outcomes.

Hypertension was associated with osteoarthritis in a Korean population analysis and accelerated cartilage deterioration through vasopressin signaling in mouse models, identifying a potential disease pathway whose therapeutic relevance in humans remains unproven.

The 2026 ESC heart failure guidelines redefine ejection-fraction phenotypes, formalize stages A through D, and broaden foundational therapy recommendations, including SGLT2 inhibitors and mineralocorticoid receptor antagonists across defined clinical settings.