Articles related to Emergency Medicine

Aniruddha Hazra, MD, of Howard Brown Health in Chicago, and colleagues found that of 90 people who tested positive for monkeypox following a single dose of Jynneos, 77% of the cases happened within 14 days of the first dose and 14% occurred within 14-28 days of the first dose. Five positive tests were returned following a second dose of the modified vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine in the eight cases that occurred 28 days after vaccine initiation.

In the US, reports of COVID-related clots have declined. But social media posts in the UK indicate a rise there – and typically what the UK reports is a harbinger of what is coming to the US.

In a randomized study involving 750 ICU patient on mechanical ventilation, minimizing sedation and employing daily physiotherapy did not yield better outcomes vs. standard care – but did increase the number of adverse events.

This study of 2,500 adults receiving mechanical ventilation randomized 1/3 were assigned to an exigent saturation target pf 90%, 1/3 to a target of 94%, and 1/3 to a target of 98%. The median number of ventilator-free days was 20, 21, and 21 for the three target groups, respectively. In-hospital death by day 28 was 34.8%, 34.0%, and 33.2% for the three groups, respectively.

According to new information revealed in a study of the AHA’s COVID-19 Cardiovascular Disease Registry, new onset AFib occurs in 5% of patients hospitalized with COVID-19. Patients who developed new-onset AFib experienced longer hospital stays and approximately 45% died during their hospitalization. Atrial fibrillation can directly increase the risk of stroke and prolong hospitalization. It is also an indirect marker of the insult that the heart is experiencing when patients are infected with COVID-19.

In this multicenter study, adult patients with status epilepticus were randomized into levetiracetam (LEV) or fosphenytoin (FPHT) as a second-line treatment after diazepam. The authors conclude that LEV may be recommended as a second-line treatment for SE along with phenytoin/FPHT.