Articles related to Hospitalist

Gabapentin has been increasingly used as part of a multimodal analgesia regimen to reduce opioid use in perioperative pain management. In this cohort study of 237,872 adults aged 65 years or older, perioperative gabapentin users had significantly increased risk of delirium, new antipsychotic use, and pneumonia compared with nonusers after major surgery.

A quartet of current clinical trials involving first-in-class molecules and CRISPR gene editing show great promise. STELLAR investigates a fusion protein in PAH, CodeBreak 200 studies a first-in-class of KRAS inhibitor, EMERGENT-2 focuses on a new treatment for schizophrenia, and NCT04601051 studies a gene editing drug for one form of amyloidosis.

In 2018, this previously high revenue-generating surgeon had a series of patient injuries and deaths resulting from his surgeries. He was removed from the surgery schedule following a whistleblower lawsuit.

Although many organizations advise reducing the range of antibiotic therapy for hospitalized patients in light of laboratory findings, some are challenging the validity of the practice. One expert argued that there are insufficiently strong data on spectrum de-escalation to determine whether it improves outcomes.

To assess short-term risk for severe cardiovascular events (excluding myocarditis and pericarditis) after COVID-19 vaccination, adults younger than 75 years hospitalized for PE, acute MI, hemorrhagic stroke, or ischemic stroke (73,325 events) were reviewed in relation to a 1st or 2nd COVID vaccine dose. No association was found between the Pfizer–BioNTech or Moderna vaccine and severe cardiovascular events. The first dose of the Oxford–AstraZeneca vaccine was associated with acute MI and PE in the second week after vaccination. An association with MI in the second week after a single dose of the Janssen vaccine could not be ruled out.

There are other methods to push learners, according to hospitalist Dr. Benjamin Kinnear. “If you want to make them feel more stressed, give them more difficult assignments or test their clinical judgment; don’t try to make them feel challenged by making them feel inferior.”