Articles related to Pediatrics

In a phase 3 trial involving 103 pediatric patients with congenital adrenal hyperplasia, crinecerfont treatment resulted in a mean reduction of androstenedione levels by 197 ng/dL after 4 weeks, compared to an increase of 71 ng/dL in the placebo group.

In a phase 2 study of nipocalimab for early-onset severe hemolytic disease of the fetus and newborn, 54% of high-risk pregnancies resulted in live births at or after 32 weeks’ gestation without intrauterine transfusions, compared to a historical benchmark of 0%.

Postpartum OCD affects 2-24% of new mothers, often manifesting as intrusive thoughts of infant harm accompanied by compulsive checking behaviors.

The 2024 U.S. SPR emphasizes the paramount importance of personal autonomy in contraceptive decision-making, particularly in light of historical and ongoing contraceptive coercion and reproductive mistreatment in the United States.

Neffy®, an FDA-approved intranasal epinephrine spray, demonstrates bioequivalence to injectable epinephrine for anaphylaxis treatment in patients weighing ≥30kg, potentially reducing barriers to rapid intervention.

Recent findings suggest that a slow up-dosing strategy in peanut oral immunotherapy for young children may offer a safer and more effective approach to managing peanut allergies.