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The New England Journal of Medicine
A study of 107 pregnant or postpartum persons with unusual prenatal cfDNA screening results found that specific genomic patterns—particularly the presence of copy-number gains and losses across three or more chromosomes—were associated with occult cancer in 95.9% of cases, suggesting potential new criteria for risk stratification.
Medical Genetics December 11th 2024
MDLinx
Mortality rates for hiatal hernia repairs vary significantly between elective (1.3%) and emergency (8%) procedures, emphasizing the importance of timely intervention when complications arise.
Emergency Medicine December 3rd 2024
Cleveland Clinic Journal of Medicine
Bevacizumab therapy demonstrated marked improvement in both epistaxis severity and abdominal symptoms, despite unchanged radiographic appearance of hepatic AVMs, suggesting therapeutic benefit at the microvasculature level.
Gastroenterology October 28th 2024
Cancer Therapy Advisor
AI-assisted diagnosis of lung cancer showed 87% sensitivity and 87% specificity in a meta-analysis, suggesting potential for improved accuracy in interpreting chest CT scans.
Oncology, Medical October 8th 2024
In a population-based trial, MRI-targeted biopsy significantly reduced the detection of clinically insignificant prostate cancer compared to systematic biopsy, without increasing the risk of advanced cancer detection. These findings support the use of MRI-targeted biopsy as a more efficient and safer screening method.
Cannonball pulmonary lesions on imaging should prompt a thorough investigation for underlying malignancy, particularly germ cell tumors.
Internal Medicine September 11th 2024