Articles related to ANTIPSYCHOTICS

The new chemical entity is an atypical antipsychotic and the active metabolite of iloperidone (Fanapt). Its ability to cross the blood-brain barrier likely contributes to iloperidone’s clinical effects.

“For most patients in the early stages of schizophrenia, symptomatic remission can be achieved using a simple treatment algorithm comprising the sequential administration of amisulpride and clozapine.” — Leucht et al, J Clin Psychiatry 2026

“Health care systems should recruit more trained psychologists and offer combinations of evidence-based pharmacotherapy and psychotherapy to patients with mood disorder, especially with suicide risk in resource-limited settings.” — Study authors, Journal of Psychiatric Research

“Evenamide has the potential to treat the symptoms of schizophrenia more broadly, addressing also those poorly managed by the currently available antipsychotics.” — Ravi Anand, MD, Therapeutic Advances in Psychopharmacology

Treatment preferences shifted to include nonaugmentative antidepressants and electroconvulsive therapy based on changes in patient characteristics.

Clozapine did not show superior efficacy compared to second-generation antipsychotics in treatment-resistant schizophrenia.