Articles related to ATRIAL FIBRILLATION (AFIB)

Medical records of more than half a million individuals in the EU, UK, and US were evaluated. Apixaban was the most frequently prescribed direct oral anticoagulant (DOAC) for AFib. It was also associated with a lower incidence of GI bleed vs. the other DOACs.

According to new information revealed in a study of the AHA’s COVID-19 Cardiovascular Disease Registry, new onset AFib occurs in 5% of patients hospitalized with COVID-19. Patients who developed new-onset AFib experienced longer hospital stays and approximately 45% died during their hospitalization. Atrial fibrillation can directly increase the risk of stroke and prolong hospitalization. It is also an indirect marker of the insult that the heart is experiencing when patients are infected with COVID-19.

When compared with rivaroxaban in a propensity score–matched cohort of 19,894 patients, apixaban was associated with an approximately 50% lower rate of ischemic stroke or systemic embolism and bleeding compared to rivaroxaban.

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A UK study reports that a history of irregular menstrual cycle was associated with higher risk for afib in women. A finding from the Vitamin D and Omega 3 Trial (VITAL) Rhythm Study reveals that when controlled for height and body size, women are at higher risk than men for afib, suggesting that biological sex and body size account for much of the protective effect of female sex. And as separately reported, early rhythm control is associated with lower risk for CV events as compared to usual care.

Exploring the Korean National Health Insurance claims database revealed that rhythm control via ablation or drugs, initiated within 1 year of diagnosis of AF, was associated with lower risk for cardiovascular events. This held true for both low risk and higher risk patients. The study analyzed data on more than 35,000 patients with a median age of 70.