Articles related to CLINICAL STUDY

The editorialists noted that, because of the slow pace of clinical trials, their findings will likely be the best available evidence for some time: “While we await better evidence, we believe that clinicians should meet patients with chronic pain ‘where they are.’ Conventional analgesic medications are effective only in a subset of persons…clinicians can compassionately witness, record, and offer guidance to help patients with chronic pain use cannabis wisely.”

In this cross-sectional study of 586 probands and 698 first-degree relatives, cannabis use disorder and bipolar disorder II in probands were associated with an independent increase in risk of cannabis use disorder in relatives; bipolar disorder I and major depressive disorder in probands were not significantly associated with cannabis use disorder in relatives. The risk of cannabis use disorder was highest among relatives with both familial and individual history of bipolar disorder II.

People who are fully vaccinated against COVID-19 have a shorter duration of viable viral shedding and a lower secondary attack rate than partially vaccinated or unvaccinated people. Data from this study provides important evidence that despite the possibility of breakthrough infections, COVID-19 vaccinations remain critically useful for controlling the spread of SARS-CoV-2.

In a 7-year study of 171,000 individuals with a mean age of 56 years, these researchers elucidate the hazard ratio for death from CVD or cancer and levels of daily coffee consumption.

The studies described in Acta Neurologica Belgica assess eight patients who developed a new-onset neuromuscular disorder following COVID-19 vaccination. “These various presentations strengthen the association between COVID-19 vaccination and particular GBS phenotypes,” the researchers noted.