Articles related to DRUG SAFETY & INTERACTIONS

This review highlights the importance of evaluating the duration of proton pump inhibitor therapy in light of its association with an increased risk of stomach cancer. Long-term use, defined as one year or more, can significantly heighten this risk, emphasizing the need for judicious use of these medications.

This “From the Editor” in the Cleveland Clinic Journal of Medicine offers a nuanced view of corticosteroid therapy, highlighting the balance between their significant therapeutic benefits and the risk of adverse effects in long-term use.

In elderly patients, the heightened sensitivity to medications necessitates a tailored approach to prescribing, focusing on minimizing risks of confusion, hypotension, and falls. Consideration of safer alternatives and non-pharmacologic interventions is essential in promoting their well-being.

Ensure patient safety and treatment efficacy with awareness of the recent recall of omeprazole and sodium bicarbonate powder, essential for treating critical gastrointestinal conditions.

In oncology, the balance between rapid innovation and patient safety is critical. The recent withdrawal of an accelerated approval cancer drug highlights the need for more stringent evidence and robust trial design to truly benefit patients.

In a comprehensive analysis of COPD patients, the use of gabapentinoids was found to be associated with a 1.39 times higher risk of severe exacerbations requiring hospitalization. This finding underscores the need for cautious prescribing of these medications in the COPD population, considering their potential respiratory risks.