Articles related to DRUG SAFETY & INTERACTIONS

Of the four most commonly prescribed antiepileptic drugs (AEDs) in the UK, carbamazepine wasn’t significantly associated with Parkinson’s, but three AEDs did have a significant relationship, including lamotrigine, levetiracetam, and sodium valproate.

Misuse of prescription stimulants was associated with prior year treatment for depression, ADHD, and substance use disorder. Identified risk factors for stimulant misuse include use of prescription drugs in the past month (5.5 times increased risk) and use of illegal drugs in the past month (8 times higher risk).

After completing this activity, participants will be better equipped to discuss the major difficulties in managing MDR HIV and to illustrate the promise of both existing and forthcoming MDR HIV medicines.

Mental health care professionals who prescribe or dispense to patients need to know the half-lives of the drugs that they prescribe, the half-lives of active metabolites — if any — how these half-lives may differ with individual patient characteristics, and how to use this knowledge to prescribe to best advantage.

When immune checkpoint inhibitor therapy was started, detectable levels of acetaminophen in the plasma were linked to significantly poorer PFS and OS. The fact that poorer clinical outcomes were demonstrated to be unrelated to other prognostic variables, such as age, performance status, the quantity of past lines of therapy, and tumor kind, is noteworthy.

The potential link between insulin resistance and bipolar disorder is causing a “paradigm shift in psychiatry,” remarked Dr. Cynthia Calkinan, associate professor of psychiatry at Dalhousie University in Halifax, Nova Scotia, Canada.