Articles related to DRUG SAFETY & INTERACTIONS

Explore the latest study revealing potential cardiovascular risks of acetaminophen even at standard dosages, which highlights the need for cautious use in chronic pain management.

In a recent clinical observation, a patient treated with dapsone for leprosy exhibited symptoms of methemoglobinemia, despite a normal Pao2 level. Such cases underscore the need for vigilant monitoring of oxygen saturation and methemoglobin levels during dapsone therapy.

For healthcare professionals managing older patients, it is essential to recognize the impact of certain medications like tricyclic antidepressants and benzodiazepines on fall risk. Reviewing and adjusting prescriptions can significantly enhance patient safety.

This review highlights the importance of evaluating the duration of proton pump inhibitor therapy in light of its association with an increased risk of stomach cancer. Long-term use, defined as one year or more, can significantly heighten this risk, emphasizing the need for judicious use of these medications.

This “From the Editor” in the Cleveland Clinic Journal of Medicine offers a nuanced view of corticosteroid therapy, highlighting the balance between their significant therapeutic benefits and the risk of adverse effects in long-term use.

In elderly patients, the heightened sensitivity to medications necessitates a tailored approach to prescribing, focusing on minimizing risks of confusion, hypotension, and falls. Consideration of safer alternatives and non-pharmacologic interventions is essential in promoting their well-being.