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Clinical Advances in Hematology & Oncology
Pirtobrutinib offers a new line of therapy for CLL and SLL patients who have progressed after covalent BTK inhibitors and venetoclax, with a significant overall response rate and manageable adverse events.
Hematology/Oncology June 17th 2024
The New England Journal of Medicine
In a recent phase 3 trial, asciminib has shown superior efficacy and safety in newly diagnosed chronic myeloid leukemia patients, achieving a higher major molecular response rate at week 48 compared to traditional tyrosine kinase inhibitors.
Hematology/Oncology June 4th 2024
Menin inhibitors, targeting the menin-KMT2A interaction, have demonstrated significant response rates in treating specific genotypes of AML and ALL, offering a new avenue for personalized leukemia therapy.
Hematology/Oncology May 20th 2024
Prompt recognition and treatment initiation are paramount in acute promyelocytic leukemia cases presenting with fever, weakness, and pancytopenia, as highlighted in this clinical analysis.
Hematology/Oncology May 6th 2024
Epcoritamab represents a significant breakthrough in the treatment of Richter syndrome, showcasing promising results in patients who have exhausted other therapeutic avenues. Its unique bispecific action heralds a new era in hematologic malignancy management.
Hematology/Oncology March 18th 2024
Cleveland Clinic Journal of Medicine
Explore a compelling case study demonstrating the intricate relationship between chronic myeloid leukemia, autoimmunity, and post-transplant hematologic complications, highlighting the importance of thorough diagnostics and tailored treatment approaches in managing complex patient scenarios.
Hematology March 18th 2024