A case of pacemaker-lead dislodgement with cardiac perforation in a 96-year-old patient highlights the importance of recognizing and addressing complications swiftly to prevent severe outcomes.

Plain black coffee has negligible calories and may aid weight maintenance, while coffee additives and caffeine’s impact on sleep and appetite can contribute to weight gain.

The updated anaphylaxis guidelines emphasize immediate epinephrine administration at the onset of symptoms and provide comprehensive recommendations for monitoring and follow-up care to prevent recurrence and improve patient education.

Early targeted palliative care consultations in the ICU can significantly increase transitions to do-not-resuscitate orders and reduce the duration of mechanical ventilation, enhancing end-of-life care.

The new guideline emphasizes early intervention and careful medication selection for pregnant patients with epilepsy, recommending lamotrigine, levetiracetam, and oxcarbazepine, while advising against valproic acid, phenobarbital, and topiramate.

Recent studies indicate that while ketamine and ECT are equally effective for treating MDD, ketamine did not prove non-inferior to ECT for MDEs. Both treatments have distinct side effect profiles that are critical for clinical decision-making.