Articles related to Family Medicine/General Practice

The results of these trials show that vitamin D reduced the risk of diabetes progression by 3% to 18% after three years, with serum 25-hydroxy D levels of at least 125 nmol/L showing the greatest benefit. Vitamin D was also associated with a 30% increase in the likelihood of returning to normal glucose regulation.

In the US, chronic pain is widespread and continues to be a burden for people, families, and society as a whole. Extreme caution should be exercised when choosing to take an opioid to treat pain. The organizations do not advocate the regular use of opiate analgesics to treat chronic pain, as the hazards to the patient outweigh the minimal benefits that opioids may offer. Buprenorphine should be taken into consideration if it is decided to employ long-term opioid therapy for a patient due to its lower risk profile. By checking for underlying mental problems and a history of traumatic brain injury, clinicians can further lower the risk. Although risk mitigation strategies have been used to reduce risk in opioid patients, the guideline development group was surprised to find little evidence in this area.

4,500 people were tracked using 24-hour monitors for 7 days. Activity levels were studied to determine the effect on short-term memory, problem-solving, and processing skills. As little as six to nine minutes of moderate-to-vigorous activity when compared to sitting, sleeping, or gentle activities yielded higher cognition scores. Cognitive improvement was modest, but increasing time spent in energetic activity increased the measured benefits.

The SGLT2 inhibitor bexagliflozin is now available under the brand name Brenzavvy. Approval was based on monotherapy trials versus glimepiride, where the new drug was non-inferior, and in combination with metformin.

The CBC, ordered hundreds of millions of times a year in the US alone, typically reports 19 different values, some of which are redundant and inconsequential. These authors suggest three distinct CBCs. [Subscription Required]

A prospective cohort study of 629 patients with non-MRI-conditional ICDs from 2003 to 2013, including 813 MRIs, concludes that the devices continue to function properly after MRI.