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HealthlineChristina Applegate and MS: Warning Signs Key to Early Diagnosis

The actress shares her personal story on symptoms, diagnosis, and the importance of early detection.


Multiple sclerosis (MS) is a complex disease with symptoms that can often be mistaken for other conditions, making early detection a challenge. This article explores the journey of actor Christina Applegate, her struggle with MS, and the importance of recognizing early symptoms for timely diagnosis and treatment.

Key Points:

  • Christina Applegate, known for her roles in Anchorman and The Sweetest Thing, was diagnosed with MS in 2021.
  • Applegate first noticed changes in her body a few years ago while shooting the first season of her Netflix show Dead to Me.
  • Experts agree that the sooner one recognizes MS symptoms, the better.
  • Symptoms could include loss of vision/blurry vision in one eye, unilateral facial pain or numbness, vertigo, new weakness or sensory changes on one side or in both legs, and with walking.
  • Early diagnosis of MS is important because we have very effective therapies that can help prevent future relapses and future disability.
  • MS symptoms aren’t always specific to the condition, making it difficult to diagnose.

You can fall, you can slip, your legs can buckle. There are just certain things that people take for granted in their lives that I took for granted. Going down the stairs, carrying things — you can’t do that anymore.
– Christina Applegate


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