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Practical Neurology
The new guideline emphasizes early intervention and careful medication selection for pregnant patients with epilepsy, recommending lamotrigine, levetiracetam, and oxcarbazepine, while advising against valproic acid, phenobarbital, and topiramate.
Neurology May 21st 2024
The New England Journal of Medicine
A 2019 trial report from NEJM offered a comparative analysis of levetiracetam, fosphenytoin, and valproate in managing benzodiazepine-resistant convulsive status epilepticus, providing essential insights into their efficacy and safety, aiding clinicians in informed decision-making.
Neurology April 2nd 2024
This study underscores the complexity of prescribing antiseizure medications during pregnancy, revealing that while topiramate and lamotrigine show no significant increase in autism spectrum disorder risk post-adjustment, valproate exposure remains a concern due to its association with a higher ASD incidence.