Articles related to BLEEDING/BLOOD DISORDERS

In this randomized trial of 1,010 patients with stable DES undergoing noncardiac surgery, perioperative aspirin continuation showed no significant reduction in major adverse cardiac events compared to complete antiplatelet cessation.

In the OPTION trial, LAAC demonstrated a 56% reduction in bleeding events compared to oral anticoagulation while maintaining equivalent stroke prevention in post-ablation patients.

In a comprehensive Bayesian network meta-analysis, 1 month of DAPT followed by potent P2Y12 inhibitor monotherapy was associated with a significant reduction in major bleeding compared to the conventional 12 months of DAPT, without an increase in MACCE.

Valoctocogene roxaparvovec gene therapy demonstrates long-term efficacy in reducing bleeding episodes and factor VIII use in patients with severe hemophilia A, potentially changing the treatment landscape for this condition.

In patients with both cirrhosis and atrial fibrillation, apixaban initiation was associated with lower rates of major bleeding compared to rivaroxaban or warfarin, without compromising thromboembolic protection.

Schistosomiasis should be considered in the differential diagnosis for patients presenting with rectal bleeding, particularly those with a history of freshwater exposure in endemic areas.