Articles related to Clinical Pharmacology

“If acetaminophen is the safest among available options but pregnant women are advised to avoid it because of the risk of ASD and ADHD in exposed offspring, then they are caught between a rock and a hard place.”

These medications can reduce blood flow through the kidneys, which can contribute to kidney damage or failure. Patients with heart failure, liver disease, or existing kidney problems are at a higher risk.

Given that human-targeted drugs are often taken continuously throughout life, not for short periods, which is the case for antibiotics, the physiological effects can be even more profound.

The FDA’s Class II designation indicates that exposure or usage of ‘a violative product may cause temporary or medically reversible adverse health consequences or where the probability of serious adverse health consequences is remote.’

The FDA says on its website that it has been investigating drugs for nitrosamines in some types of medications, noting they’re common in water and foods. But the agency noted that such impurities have been linked to an increase in cancer in individuals who are exposed to elevated levels and over long periods of time.

Across the board, for all outcomes—acute pancreatitis, all-cause mortality, hospitalizations, ICU admissions—we saw significant reductions in patients on GLP-1s compared to chronic pancreatitis patients not on these drugs.” – Mahmoud Y. Madi, MD