Articles related to Hematology/Oncology

A good primer for the oncologist on several cancer screening tests that can be administered at home and help detect cancer in its earliest, most treatable stages — often before people experience symptoms. Some tests, such as a screening colonoscopy, can even treat cancer by removing abnormal cells before they become problematic.

The incredible story of how a young mother of two children survived and ultimately overcame colon cancer that had spread throughout her body. Despite suffering severe anemia, diarrhea and emesis, and losing 25 pounds, this determined woman beat the odds.

This Children’s Oncology Group report recommends new guidance on administering radiotherapy among children with cancer. Questions are answered around imaging protocols, dose reduction, setup correction, and adaptive therapy.

A study published in Blood Advances finds that higher levels of NETosis in myeloproliferative neoplasms (MPNs) are not linked to thrombotic events. The study determined that while NETosis may play a role in facilitating thrombosis, it is not a sole causative determinant in MPN-associated thrombophilia.

In ASH Clinical News, Dr. Geoffrey Uy, a professor in the Oncology Division at Washington University School of Medicine in St. Louis, discusses treatment options for a transplant-ineligible patient who has Philadelphia chromosome-positive (Ph+) acute lymphocytic leukemia (ALL). The patient under review is a 61-year-old female diagnosed with Ph+ ALL who has multiple comorbidities and is not a candidate for allogeneic hematopoietic cell transplantation.

Bone marrow failure in children and young adults is often suspected to be inherited; however, in many cases, diagnosis remains uncertain. A new study involving 179 patients (from 173 families) found that implementing precision medicine at diagnosis can improve patient management, along with the use of family counseling. This study published in Blood expands the “portrait” of IBMF syndromes and explores some newly recognized disease entities.