Articles related to Nephrology

Studies on fluid restriction in patients with HF are scarce, and most of the available studies are at high risk of bias. Although power is lacking, there is no evidence indicating that fluid restriction affects mortality or HF hospitalizations, but there is a signal of harm in terms of thirst distress.

The researchers discovered that findings among older adults reinforced the guideline shift toward personalized, risk-based care.

“People who maintain low levels of LDL-C and triglycerides at earlier ages are much less likely to develop atherosclerotic disease decades later.” — Pamela B. Morris, MD, FACC, FAHA, guideline writing committee vice-chair

“CHIP, especially non-DNMT3A CHIP, was independently associated with incident HF. Future research should explore the gene-specific mechanisms by which CHIP variants promote HF in humans.” — Study Authors, JAMA Cardiology

“Patients hospitalized for HFrEF in US clinical practice are at very high risk of poor clinical outcomes, even when prescribed quadruple medical therapy.” — Dr. Stephen J. Greene, Duke Clinical Research Institute

These medications can reduce blood flow through the kidneys, which can contribute to kidney damage or failure. Patients with heart failure, liver disease, or existing kidney problems are at a higher risk.