Articles related to Neurology

Swedish researchers have learned how to “grow” electrically conductive regions in tissue. The process involves injecting an enzyme-rich hydrogel into target tissues. The enzymes interact with molecules in the tissue and change the structure of the gel to make it conductive. The technique has potential application in areas as diverse as cardiac pacing to brain-computer interface development – all without the implanted electrodes that are used today and the physical limits they impose.

Drawing from animal evidence that aging and metabolic dysfunction result in depletion of NAD+ within neurons, B3 supplementation of 500mg BID for 6 weeks was studied as a means of increasing available NAD+. As published in Nature, a small but significant increase in NAD+ available to neurons was seen with B3 supplementation.

Symbyx Neuro uses a 12-minute cycle of red light therapy followed by 12 minutes of infrared light therapy. Improvement was seen across measures of facial expression, upper limb, walking, and tremor domains. Light therapy may reduce Parkinson’s symptoms by targeting mitochondria and/or the release of dopamine. It does not interfere with other Parkinson’s treatments.

Nearly 25% of fentanyl powder seized in 48 states in 2022 contained xylazine. Xylazine causes severe injection site wounds that can require amputation and puts drug users at higher risk for overdose and death.

Two-hundred sixteen (216) people with mild-to-moderate disease were treated with 100 mg simufilam tablets twice daily for 12 months. ADAS-Cog-11 score showed a “highly desirable” overall minimal decline in cognitive ability after one year. Simufilam is an oral small molecule designed to to prevent beta and tau amyloid clumping by correctong an altered form of filamin A.

Genetic mutations, head trauma, and other PD causes are well known or easily identified. However, these causes and risk factors cannot account for the majority of cases. This six-atom molecule that can decaffeinate coffee, degrease metals, and dry clean clothes was identified as a possible PD contributor as early as 1969.