Articles related to Oncology, Medical

New-onset diabetes in patients over 50 may serve as an early warning sign of pancreatic cancer, with research showing a 1-3 year presence of diabetes before cancer diagnosis in many cases.

A study of 107 pregnant or postpartum persons with unusual prenatal cfDNA screening results found that specific genomic patterns—particularly the presence of copy-number gains and losses across three or more chromosomes—were associated with occult cancer in 95.9% of cases, suggesting potential new criteria for risk stratification.

The discovery of I-NCMs’ ability to simultaneously patrol blood vessels and infiltrate tumor environments opens new possibilities for treating therapy-resistant cancers.

Workplace exposure to harmful chemicals remains a significant risk factor for bladder cancer, particularly affecting specific occupations and requiring targeted prevention strategies.

Durvalumab consolidation therapy demonstrated unprecedented survival benefit in limited-stage SCLC, extending median overall survival by nearly two years compared to placebo.

Poor metabolizers of UGT1A1 face a significantly increased risk of severe neutropenia from irinotecan therapy, making genetic testing crucial for appropriate dose modification.