Articles related to CLINICAL STUDY

The optimal dose of daily steps—the amount with the greatest dementia risk reduction—was 9,826 steps, with the minimum step dose, or the amount at which dementia risk was half of the maximal reduction, was 3,826 steps per day. See the original article on JAMA Neurology.

This single-center observational study sought to assess the diagnosis of somatic symptom disorder (SSD) in patients with unexplained neurological symptoms occurring in the setting of long COVID. Fifty patients were included in the study. SSD diagnosis based on DSM-5 criteria was positive in 32 (64%) patients. In the remaining 18 patients, SSD was considered possible given the high score on diagnostic scales.

A multi-variate analysis published in Cancer Medicine, which includes a population of more than 150,000 individuals, suggests that prior cannabis use was associated with a reduced risk of renal cell carcinoma and bladder cancer in women and prostate cancer in men. A potentially conflicting finding was increased risk of some cancers in current cannabis users.

This large surgically staged cohort of high-risk patients with preoperative PSMA PET evaluated the accuracy of Ga-68-PSMA-PET/CT for primary nodal staging. The findings suggest that total lesion uptake values could provide valuable presurgical staging information and might aid in predicting risk of lymph node metastasis in patients with prostate cancer.

This summary of a study from Johns Hopkins University says it might just matter how you take your pills – with special implications for bedridden or sedentary patients.

The authors engaged in research to attempt to identify circulating biomarkers for pancreatic NETs, to improve tumor surveillance and quality of life. They examined the expression of circulating miRNA in the serum of MEN1 patients and found an inverse relationship between miR-3156-5p and MORF4L2 expression, representing a potential serum biomarker that could facilitate the detection of NET occurrence in MEN1 patients.