Articles related to GENOMICS

“CHIP, especially non-DNMT3A CHIP, was independently associated with incident HF. Future research should explore the gene-specific mechanisms by which CHIP variants promote HF in humans.” — Study Authors, JAMA Cardiology

“Now that we have a treatment for genetic deafness, our hope is that this will spur universal genetic testing in all kids with hearing loss.” —Lawrence Lustig, MD, CHORD study investigator

“The variants we saw have been part of the human genome for a very long time, but the modern chemical environment is new, and we’re beginning to understand how these interactions might influence conditions like endometriosis.”

The results of PROfound and PROpel underscore the importance of identifying the genomic characteristics of the patient and the cancer to guide the selection of the most appropriate treatment for a specific patient type.

The prevalence of HRR deficiencies has been found to be as high as 20% to 30% in patients with mCRPC, a significantly higher rate than that in patients with localized disease.

Although genomic classifier tests for prostate cancer show promise, a systematic review of 22 studies reveals marked differences between observational and trial data in how these tests influence risk stratification and treatment selection.