Articles related to NEUROLOGICAL DISORDERS

Some studies in children have reported a relationship between antidepressant use in pregnancy and neurodevelopment disorders after birth. In this analysis of 145,702 antidepressant-exposed and 3,032,745 unexposed pregnancies, crude results suggested up to a doubling in risk of neurodevelopmental outcomes. Significantly, however, no association was observed after balancing for confounding variables.

Neurologic complications of COVID are leading to an increase in demand for both acute and long-term neurologic evaluation and management. Doctors Koralnik, Liotta, and Graham have been investigating the pathogenic mechanisms of acute and long-term COVID-19 and discuss here their guideline on managing neurologic complications of COVID.

Reported neurologic complications of monkeypox include headaches and mood disturbances, and more rarely, encephalitis, transverse myelitis, and seizures. Historically neurologic complications of smallpox include encephalitis, transverse myelitis, and acute disseminated encephalomyelitis among others. Of concern is the possibility of viral persistence and systemic complications in immunocompromised individuals. Monkeypox should be considered when these neurologic symptoms are seen in high-risk populations.

This single-center observational study sought to assess the diagnosis of somatic symptom disorder (SSD) in patients with unexplained neurological symptoms occurring in the setting of long COVID. Fifty patients were included in the study. SSD diagnosis based on DSM-5 criteria was positive in 32 (64%) patients. In the remaining 18 patients, SSD was considered possible given the high score on diagnostic scales.

Adult-onset genetic disorders may present with clinical and brain imaging features suggestive of acquired inflammatory diseases. An ever-growing number of potentially treatable adult-onset genetic neuroinflammatory disorders have been described in the past few years that need to be rapidly identified. This review aims to provide insights to neurologists so they can confirm a diagnosis early, when some of these genetic disorders can be successfully treated.

Neuroleptic malignant syndrome (NMS), which has a high morbidity and death rate, is one of the deadly side effects of antipsychotic or antiemetic drugs. The common drugs linked to NMS are identified in this article, along with the etiology of the condition, clinical symptoms, risk factors, laboratory and imaging results, and treatment options.