Articles related to PARKINSON'S DISEASE (PD)

People with metabolic syndrome had a 24 percent higher risk of PD than individuals without MetS, and exercise helps control MetS while improving muscle strength, coordination, and balance—plus it helps the brain develop protective mechanisms.

ImP appeared capable of entering systemic circulation, reaching the brain, and contributing to the loss of dopaminergic neurons… Treating mice with an mTORC1 inhibitor significantly reduced neuroinflammation, neuronal loss, and alpha-synuclein aggregation.

The findings stress the importance of diagnosis timing in neurodegenerative risk modeling and suggest that both early-life exposures and recent comorbidities contribute to disease vulnerability.

For a virus that was thought to be harmless, these findings suggest it may have important effects, in the context of Parkinson’s disease. It may influence how Parkinson’s develops, especially in people with certain genetic backgrounds.

This combination of Parkinsonism and polytrauma provides a powerful example of how neurodegeneration can be compounded by structural damage, with each element worsening the other.

Blood-based mitochondrial DNA testing could provide a less invasive alternative to spinal taps for Parkinson’s diagnosis, with implications for earlier intervention and treatment.