Articles related to PARKINSON'S DISEASE (PD)

Caregiver burden is common, cumulative, and often unspoken, manifesting as fatigue, depression, irritability, and social withdrawal.

Twelve months after transplantation with the lower dose, mean scores decreased by 30.6 points during off time (a 52.82% improvement from baseline) and by 12.9 points during on time (a 54.67% improvement).

People with metabolic syndrome had a 24 percent higher risk of PD than individuals without MetS, and exercise helps control MetS while improving muscle strength, coordination, and balance—plus it helps the brain develop protective mechanisms.

ImP appeared capable of entering systemic circulation, reaching the brain, and contributing to the loss of dopaminergic neurons… Treating mice with an mTORC1 inhibitor significantly reduced neuroinflammation, neuronal loss, and alpha-synuclein aggregation.

The findings stress the importance of diagnosis timing in neurodegenerative risk modeling and suggest that both early-life exposures and recent comorbidities contribute to disease vulnerability.

For a virus that was thought to be harmless, these findings suggest it may have important effects, in the context of Parkinson’s disease. It may influence how Parkinson’s develops, especially in people with certain genetic backgrounds.