The FDA has withdrawn its authorization for use of the monoclonal antibody sotrovimab in the treatment of COVID-19 in regions with a high frequency of the Omicron BA.2 subvariant. Data show that the authorized dose of the monoclonal antibody — 500 mg — is unlikely to be effective against the BA.2 COVID-19 subvariant.

Habitual alcohol consumption at all levels has been found to increase the risk of cardiovascular disease. However, the relationship between level of consumption and risk is not linear, and at lower consumption levels, other lifestyle patterns have mitigating effects.

An analysis by an Australian physician is making waves by suggesting that an infamous study of vitamin C treatments for sepsis may be fraudulent. The study author alleges that the pre- and post-comparison groups involved in the 94-patient study were too similar to be realistic and that the data were fabricated.

Diabetes medications, such as metformin, have glucose-independent effects on the male reproductive system. However, until now, it was unknown if these effects lead to birth defects in offspring. This study concludes that metformin intake in men is associated with major birth defects, particularly genital birth defects in boys.

Parallels and distinct features among paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) are discussed against the background of thrombosis, complement activation via eculizumab, and potential complement diagnostic and therapeutic avenues.

More doctors than ever are building a public presence and sharing their expert perspectives with the American public, almost creating themselves as “celebrities.” Still, their influence cannot be understated. Here are seven of the most influential, according to Healthgrades. Our guess is you’ve probably heard of a few.