Articles related to Endocrinology, Diabetes, Metabolism

Up to this point, individuals with non-alcoholic fatty liver disease (NAFLD) and a normal BMI have often been overlooked. It was assumed their normal BMI equated to a lower risk of more serious conditions than those who are overweight or obese. These findings indicate that lean patients with NAFLD are 50% more likely to have a CVA compared with overweight patients, and 10 to 30% more likely to experience CVD.

This broad review of recent studies in women’s health topics aims to help the primary care physician in discussing and guiding therapy for women in topics from cardiovascular disease to pelvic pain. The review covers such questions as: How does migraine with aura affect CVD risk in women? How do you respond to patient questions about fracture risk and bisphosphonates? Are antidepressants safe for women who are considering pregnancy? Is gabapentin effective for chronic pelvic pain?

The obesity epidemic affects millions of patients around the world, but a new treatment option may be a game-changer for the treatment landscape. Lead author of the STEP 8 clinical trial, Dr. Domenica Rubino, shares insights from trial and how these key clinical findings could change obesity management.

This “Clinician POV” with Joshua Strauss, MD, a hematologist-oncologist with Advanced Care Hematology & Oncology Associates in New Jersey, discusses the available formulations of parenteral iron and their respective risks for hypophosphatemia, patient- and disease-related factors of the condition, administration of the formulations, monitoring, and more.

Data on more than 200,000 individuals revealed that non-SSRI antidepressants were associated with a two-fold increased risk of coronary heart disease, cardiovascular mortality, and all-cause mortality at ten years. There was also evidence that SSRIs were associated with lower rates of hypertension and diabetes.

Nearly 20,000 mother-child pairs were tracked over a median follow-up of 4 years. After adjusting for maternal risk factors and their children’s own ultra-processed food intake, physical activity, and sedentary time, maternal consumption of ultra-processed foods during the child-rearing period was associated with overweight or obesity in offspring with a 26% higher risk in the group with the highest maternal ultra-processed food consumption.