Articles related to Medical Genetics

The results underscore a clear message: timing and patient selection are key — and early diagnosis and intervention make the biggest difference.

Current smoking was the most important predictor for a detrimental effect of aspirin on cancer incidence, whereas CHIP was the most important predictor for a beneficial effect of aspirin, followed by age and a family history of cancer.

For a virus that was thought to be harmless, these findings suggest it may have important effects, in the context of Parkinson’s disease. It may influence how Parkinson’s develops, especially in people with certain genetic backgrounds.

“The team found that people with Chiari malformation share more shape traits in common with Neanderthals than do people without the malformation… indicating that some people today have Neanderthal genes that affect their skull shape.”

This combination of Parkinsonism and polytrauma provides a powerful example of how neurodegeneration can be compounded by structural damage, with each element worsening the other.

“The damage to DNA lasts a lifetime. Probably the biggest concern is the increased risk of other cancers developing as a result of exposure to prior chemotherapy.”