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The New England Journal of Medicine
This article poses questions surrounding the ethical challenges in brain research, highlighting the need for post-trial care responsibilities and privacy protections as neurotechnologies advance.
Neurology July 3rd 2024
Chiari malformation type 1 is marked by cerebellar tonsils descending below the foramen magnum, often causing headaches, paresthesia, and CSF flow obstruction. Early diagnosis and appropriate surgical intervention can significantly improve patient outcomes.
This study reveals that individuals with autosomal dominant Alzheimer’s disease who are heterozygous for the APOE3 Christchurch variant experience a median delay in cognitive impairment onset of approximately five years compared to those without the variant.
GoodRx Health
Identifying early symptoms like loss of smell and constipation can lead to a timely diagnosis of Parkinson’s disease, facilitating earlier intervention and potentially slowing disease progression.
In a Chinese study, tenecteplase administered 4.5 to 24 hours after stroke onset resulted in less disability at 90 days compared to standard treatment, though it carried a higher risk of symptomatic intracranial hemorrhage.
In a randomized trial of 1,412 patients with acute ischemic stroke, reteplase was more likely to result in excellent functional outcomes at 90 days compared to alteplase.