Articles related to Pediatrics

Children actively construct their understanding of the world through distinct developmental stages, each characterized by qualitative differences in cognitive processing rather than simply accumulated knowledge.

Analysis of more than 5 million adolescent insurance claims reveals that gender-affirming medication prescriptions remain exceptionally rare, with peak rates reaching only 140.16 per 100,000 at age 17 for AFAB adolescents.

Drug poisoning has emerged as the leading cause of death among young adults since 2014, with nearly 80% of deaths in 2022 involving both heroin and fentanyl.

The phase 3 ALLELE trial demonstrated tabelecleucel’s potential with a 50.7% overall response rate and median duration of response of 23.0 months in EBV+ PTLD patients.

Antiviral therapy initiated within 48 hours of symptom onset can reduce illness duration by 1-2 days, highlighting the importance of early recognition and intervention in high-risk populations.

Rapunzel syndrome represents a complex intersection of psychiatric and gastrointestinal pathology, often remaining asymptomatic for years before presenting with serious complications.