Articles related to Pediatrics

Sleep midpoint variability, duration variability, and social jetlag were each associated with lower receptive vocabulary and visuospatial memory scores in 379 preschool-age children, with executive attention unaffected by any sleep regularity measure.

Each additional hour of daily digital screen exposure was associated with 21% higher odds of myopia in a 335,524-participant meta-analysis, with the steepest odds increase observed between 1 and 4 hours of daily exposure, though substantial heterogeneity and cross-sectional study designs precluded causal conclusions.

A 21-element enhanced recovery protocol implemented across 18 US hospitals reduced inpatient opioid use by 56% in children undergoing GI surgery, with patients receiving 13 or more protocol elements averaging one fewer hospital day and half the complication risk.

A phase 3 randomized trial of 449 children with intracranial ependymoma found no significant event-free or overall survival benefit from adding maintenance chemotherapy after radiation, while molecular markers — particularly 1q gain and 6q loss — identified a high-risk posterior fossa subgroup with substantially worse outcomes.

The 2026 Surviving Sepsis Campaign pediatric guidelines issued 61 recommendations covering infection recognition, hemodynamics, ventilation, and long-term follow-up for children with sepsis or septic shock.

The FDA has approved an OTC switch for adapalene/benzoyl peroxide gel (Differin Epiduo) for patients 12 and older, expanding adolescent access to a fixed-dose retinoid combination without a prescription or clinical visit.