Articles related to ATRIAL FIBRILLATION (AFIB)

Standard physician-directed medical care, including blood thinners for eligible patients, remains a valid management option for those older patients with irregular heartbeat who are at very high risk for stroke and bleeding.

HF was independently associated with a 30% to 50% higher IS rate in 2007 to 2010, but this association attenuated to only 10% to 15% higher in 2015 to 2018.

“Catheter ablation reduced risks for ischemic stroke after 30 days (relative risk 0.63), mortality (RR 0.73), and heart failure hospitalization (RR 0.68), but increased ischemic stroke risk at or before 30 days (RR 6.81).”

The analysis demonstrates that periprocedural bleeding rates with factor XI inhibition were comparable to or lower than traditional anticoagulation, with only 0.9% of procedures within 30 days of abelacimab dosing experiencing major bleeding complications.

ARREST-AF offers very promising insight into the potential efficacy of complete risk-factor modification.

In this 22-center study of repeat ablations following PFA, 45% of patients maintained complete pulmonary vein isolation from their initial procedure, with subsequent success rates varying significantly by arrhythmia type.