Articles related to CARDIOVASCULAR DISEASE (CVD)

This study evaluates the use of statins for primary prevention of cardiovascular diseases in adults aged 75 years and older, demonstrating a significant reduction in CVD incidence without an increase in severe adverse events. These findings provide real-world evidence to guide clinical decision-making in this underrepresented population.

The phase 3 trial of aficamten for symptomatic obstructive hypertrophic cardiomyopathy showed a significant improvement in peak oxygen uptake compared to placebo, with meaningful enhancements in patient-reported outcomes and clinical measures.

Lower baseline testosterone and hormonal imbalances, including low SHBG and DHT levels, are significantly associated with increased all-cause and cardiovascular mortality in aging men.

Cardiac amyloidosis often presents with nonspecific symptoms and requires a high index of suspicion and specialized diagnostic protocols to ensure accurate diagnosis and effective management.

Recent research indicates an incremental risk of cardiomyopathy associated with extended stimulant use in ADHD treatment among young adults. Notably, this risk peaks at eight years of therapy, reinforcing the need for vigilant cardiovascular monitoring.

In cases of transthyretin-mediated amyloid cardiomyopathy, standard diagnostic techniques may not always detect cardiac abnormalities, as evidenced by a patient with the rare Tyr78Phe mutation who lacked typical imaging markers but confirmed amyloid deposits through biopsy.