Articles related to CLINICAL STUDY

This study provides evidence that older patients with Binet stage A CLL, including those in the oldest age groups, can receive the Chronic Lymphocytic Leukemia International Prognostic Index (CLL-IPI). Because of the high median age in our study, we were also able to identify a relationship between del(17p) and age, which raises the possibility that age-adjusted prognostic tools could enhance CLL prediction. In cardiology, risk stratifications and recommendations for antilipid treatment have long taken into account the interaction between age and other risk factors for fatal cardiovascular disease, but in CLL, age is typically only considered as an additive factor in prognostic models.

Aniruddha Hazra, MD, of Howard Brown Health in Chicago, and colleagues found that of 90 people who tested positive for monkeypox following a single dose of Jynneos, 77% of the cases happened within 14 days of the first dose and 14% occurred within 14-28 days of the first dose. Five positive tests were returned following a second dose of the modified vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine in the eight cases that occurred 28 days after vaccine initiation.

In a randomized study involving 750 ICU patient on mechanical ventilation, minimizing sedation and employing daily physiotherapy did not yield better outcomes vs. standard care – but did increase the number of adverse events.

Pregnant women who filled prescriptions for bupropion, citalopram, escitalopram, fluoxetine, or sertraline during pregnancy (antidepressant-exposed cohort) and pregnant women who did not fill an antidepressant prescription within 90 days of the start of their pregnancy through delivery (control group) were the subjects of the study conducted by researchers from Brigham and Women’s Hospital in the United States. The main finding concerned the frequency of ADHD, autism spectrum disorder (ASD), behavioral disorder, developmental coordination disorder, developmental speech or language disorder, intellectual disability, any NDDs, and specific learning disorders among the children of the women in the study.

In an article originally published in JAMA Neurology, the authors state that long-term clinical and cinematic follow-up point to young-onset tremor-dominant idiopathic Parkinson’s disease rather than boxing injury.

The authors determined the prognostic significance of CTC enumeration and the evolution of both CTC enumeration and the HP ratio over time in the largest longitudinal CTC study in mRCC to date. Potential biomarkers to predict and track response to immunotherapy in mRCC are provided by these insights into changes in both tumor burden and the molecular profile of tumor cells in response to various treatments.