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Nearly half of behavioral variant frontotemporal dementia patients initially receive a psychiatric diagnosis, highlighting the critical need for improved diagnostic approaches.

In a population-based trial, MRI-targeted biopsy significantly reduced the detection of clinically insignificant prostate cancer compared to systematic biopsy, without increasing the risk of advanced cancer detection. These findings support the use of MRI-targeted biopsy as a more efficient and safer screening method.

Primary CNS vasculitis affects an estimated 2.4 cases per 1 million person-years, presenting a significant diagnostic and therapeutic challenge for neurologists and rheumatologists.

Early diagnosis of mesenteric ischemia remains a clinical challenge due to its often vague symptoms, but timely imaging and high clinical suspicion are key to preventing catastrophic outcomes.

Cannonball pulmonary lesions on imaging should prompt a thorough investigation for underlying malignancy, particularly germ cell tumors.

Diabetic retinopathy is the only leading cause of blindness that has not experienced a decrease in age-standardized prevalence between 1990 and 2020, highlighting the urgent need for improved prevention and management strategies.