Articles related to MEDICAL DIAGNOSTICS

Explore the recent identification of two distinct neurophysiological subtypes of major depressive disorder, a key advancement that could refine your approach to personalized treatments in mental health.

Gadoquatrane, a promising GBCA, enters Phase 3 clinical testing, potentially offering safer MRI procedures and advancing diagnostic capabilities for patients with CNS disorders, including MS.

Artificial intelligence, especially computer vision, could revolutionize gastroenterology by improving diagnostic accuracy, streamlining care, and paving the way for scientific advancements in disease analysis and therapy sequencing.

Enhancing Cardiovascular Disease Risk Prediction: Comparing Coronary Artery Calcium and Polygenic Risk Scores A Northwestern University study revealed that both coronary artery calcium and polygenic risk scores significantly influence 10-year risk prediction for coronary heart disease. However, coronary artery calcium score demonstrated superior predictive power, reinforcing the integration of these novel tools in risk prediction models. “What this study says is that in white participants enrolled in 2 observational studies, identifying coronary calcium predicted future cardiac events better than our currently available polygenic risk scores.” Dr. Karol E. Watson, PhD, professor of medicine and cardiology at the David Geffen School of Medicine at the University of California Los Angeles

Dopaminergic Dysfunction: A Key Player in Parkinson’s Disease Motivational Symptoms This study reveals a significant link between dopaminergic dysfunction and the emergence of motivational symptoms in Parkinson’s disease. Striatal DAT imaging emerges as a potential tool for predicting apathy/anhedonia risk, opening new avenues for intervention strategies.

Navigate the complex world of diagnosing Chiari malformation in this insightful review of a clinical case. To understand Chiari malformation, let’s explore a clinical case. A mid-30s patient with a migraine history came to the ED with a sudden posterior headache. Accompanied by transient total body numbness, loss of coordination, and an inability to swallow with drooling, these symptoms started abruptly after violent sneezing. Although neurological symptoms faded after 20 seconds, the headache persisted. Regarding vital signs and physical examination, everything was normal. The patient had a head CT ordered. Interpreting the clinical picture and CT images with care is crucial in these cases. Even though a sudden onset headache could signify a ruptured berry aneurysm, no blood was detected on the CT cuts, minimizing that concern. Remember, an LP is seldom recommended if the CT is performed within 6 hours and hemoglobin exceeds 10 g/dL. However, the clinical presentation in this case, characterized by headache and drooling, didn’t match a typical migraine. Be mindful that many patients might loosely use the term “migraine” for any severe headache. The CT cut revealed a brainstem compressed by the cerebellum, indicative of a Chiari malformation type 1. Chiari malformation, characterized by an […]