Articles related to Family Medicine/General Practice

A new Endocrine Society guideline favors watchful waiting over immediate evaluation for many girls with early breast development, narrows brain MRI and genetic testing to select cases, and sets age limits for stopping GnRH agonist therapy.

PCOS was associated with significantly elevated risk for breast, uterine, ovarian/fallopian tube, and cervical cancers in a matched cohort of more than 2.5 million women.

Premature menopause was linked to a 40% higher long-term risk of coronary heart disease in a pooled analysis of more than 10,000 women followed across six cohort studies.

Menopausal hormone therapy users showed significantly higher bone mineral density at the spine and hip than non-users in a retrospective cohort of 387 postmenopausal women.

Hormone therapy status was associated with differences in diet, physical activity, and sleep guideline adherence in a cross-sectional analysis of more than 10,000 women.

The FDA approved olezarsen (Tryngolza), an apoC-III antisense inhibitor, as an adjunct to diet for reducing triglycerides and acute pancreatitis risk in adults with severe hypertriglyceridemia, based on phase 3 data showing an 85% reduction in pancreatitis events compared with placebo.