Articles related to Oncology, Surgical

The DESTINY-Breast06 trial demonstrates the potential for earlier use of trastuzumab deruxtecan in HR+, HER2-low, and HER2-ultralow advanced or metastatic breast cancer, with significant improvements in progression-free survival compared to conventional chemotherapy.

Basal cell carcinoma, while common, rarely leads to death when detected and treated early. Physicians should be aware of the seven warning signs that can be mistaken for harmless skin conditions.

Infections account for over 50% of nonrelapse deaths in CAR T-cell therapy patients, outweighing therapy-specific toxicities like ICANS and CRS.

MCED tests aim to detect multiple cancer types through a single blood test, potentially simplifying cancer screening and expanding detection capabilities. However, their implementation raises critical questions about evidence standards and evaluation methods.

PBMs’ vertical integration allows them to dictate cancer treatment decisions, from drug selection to delivery methods, potentially compromising patient care and increasing costs.

The 2024-2025 cancer care rankings incorporate outpatient outcomes and refine criteria for high-risk patient transfers, aiming to provide a more comprehensive evaluation of cancer care quality.