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Trilaciclib (Cosela, G1 Therapeutics), a cyclin dependent kinase 4/6 inhibitor, is already approved in the United States to reduce frequency of chemotherapy-related bone marrow suppression among adults with extensive-stage small cell lung cancer. Now, the FDA has granted fast track designation to the drug for use in combo with chemo for treatment of locally advanced or metastatic TNBC.
Internal Medicine July 26th 2021
Healthgrades for Professionals
According to a study of 135,000 doctors by Doximity, male physicians made, on average, 28% more than females in 2020, a 3% increase from the 2019 numbers. The survey, along with Medscape’s poll in 2021 that showed male specialist physicians overall making 33% more than females, points to a few other large gender pay gaps, as well as some in which women doctors make salaries closer to those of men.
Allergy & Immunology July 19th 2021
There are several reasons why the COVID-19 Delta variant – responsible for the COVID crisis in India – has public health experts and doctors concerned, including its transmissibility and disease severity. You likely already know the Delta “variant of concern” is more contagious than previous variants (denoted by the Greek alphabet), but here are five other important details you should be aware of.
Allergy & Immunology July 6th 2021
JAMA Network
This Original Investigation from JAMA Network Open assesses whether clinically used markers of breast cancer, such as tumor size, tumor grade, progesterone receptor status, and Ki-67 status, are associated with long-term (25-year) survival as they are with short-term survival. The study was a secondary analysis of data from a subset of 565 women who participated in the Stockholm tamoxifen (STO-3) trial from 1976 to 1990.
Internal Medicine July 6th 2021
In this JAMA Oncology Narrative Review, the authors attempt to discover whether cardiovascular risks may be associated with the multimodal approach, including systemic therapies and breast radiotherapy (RT), in treating breast cancer patients. Although recent advancements in breast cancer treatment have led to a decrease in mortality rates, the prevalence of survivors with a potentially high CV disease risk has increased.
Cardiology June 21st 2021
This podcast/article on KevinMD.com by Syad Nishat, a partner at the Wall Street Alliance Group, offers tips and advice for the physician on estate planning, which is one of the most neglected aspects of financial planning. However, its complexity and unpredictability shouldn’t stop you from talking to a financial advisor to best prepare yourself and your family for the unexpected.
Allergy & Immunology May 12th 2021