Articles related to AUTOIMMUNE DISORDERS

Salt-and-pepper skin pigmentation can be an early indicator of systemic sclerosis, characterized by vitiligo-like depigmentation with sparing of perifollicular areas.

En coup de sabre, a linear subtype of localized scleroderma, can progress beyond the skin to involve the orbits and brain, necessitating neuroimaging in affected patients.

Chilblain lupus erythematosus can present with atypical features, such as nasal involvement, in addition to the more common acral lesions.

Researchers have identified insufficient activation of the aryl hydrocarbon receptor (AHR) pathway as a key driver in lupus pathogenesis, offering a new target for therapeutic intervention.

In a recent study, 95% of ITP patients treated with the novel anti-CD38 monoclonal antibody, CM313, achieved two consecutive platelet counts of at least 50×10^9 per liter within just eight weeks, highlighting the therapy’s efficacy and rapid action.

Hashimoto’s Thyroiditis is linked to a complex array of symptoms ranging from thyroid enlargement and systemic metabolic disruptions to severe fatigue and cognitive decline, highlighting the need for comprehensive diagnostic strategies and personalized treatment plans.