Articles related to AUTOIMMUNE DISORDERS

Explore a compelling case study demonstrating the intricate relationship between chronic myeloid leukemia, autoimmunity, and post-transplant hematologic complications, highlighting the importance of thorough diagnostics and tailored treatment approaches in managing complex patient scenarios.

This study delineates a clear association between SARS-CoV-2 infection and an elevated incidence of autoimmune inflammatory rheumatic diseases, emphasizing the necessity for healthcare providers to be vigilant in monitoring patients recovering from COVID-19 for signs of autoimmune complications.

Understanding the MTHFR gene mutation can significantly impact patient care, especially when prescribing folic acid supplements or fortified foods. Learn how this mutation affects folate metabolism and the increased risks for various health conditions.

Explore the intriguing connections between postural orthostatic tachycardia syndrome (POTS) and autoimmune disorders. This comprehensive review offers insights into diagnosis, potential autoimmune mechanisms, and future directions in the field, providing valuable information for practitioners dealing with this complex condition.

Despite striking parallels in symptomatology between POTS and autoimmune disorders, a deeper scrutiny reveals that this overlap may not be sufficient to definitively attribute an autoimmune cause to POTS; hence, indiscriminate application of immunosuppressive therapies should be re-evaluated.

Researchers discovered that inhibiting the activity of the fumarate hydratase enzyme in macrophages (a type of immune cell that plays a key role in inflammatory disorders) increased the cells’ production of interferon-beta. They also discovered that lupus patients’ macrophages have abnormally low levels of fumarate hydratase. These findings suggest that dysregulation of this enzyme may be a factor in the development of lupus, and that fumarate hydratase could be a potential therapeutic target.