Articles related to Endocrinology, Diabetes, Metabolism

High levels of xylitol, a sugar substitute commonly used by diabetic patients, may increase the risk of heart attack and stroke, according to a Cleveland Clinic study.

The Body Roundness Index (BRI) may offer a more precise alternative to BMI, correlating strongly with mortality risk and providing a clearer picture of central adiposity’s impact on health.

Hypomagnesemia, prevalent in patients with type 2 diabetes and those in intensive care, is often underdiagnosed due to nonspecific symptoms and lack of routine serum magnesium measurements.

Stopping GLP-1 drugs can lead to significant weight regain and increased appetite. Understanding the biological mechanisms and preparing patients for these changes is crucial for effective management.

In a phase 2b trial, plozasiran significantly reduced fasting triglyceride levels at 24 weeks in patients with mixed hyperlipidemia, with the 50 mg quarterly dose achieving a mean reduction of 62.4 percentage points. This study highlights the potential of APOC3 inhibition as a therapeutic strategy for lipid management.

A study in Nature Aging suggests that certain nutrients in the Mediterranean diet may slow brain aging. Key nutrients include omega-3 fatty acids, carotenoids, and vitamin E, which are linked to better cognitive function and brain health.