Articles related to Family Medicine/General Practice

A 29-year-old woman bought a genetic test that includes BRCA analysis. She comes to you with the results and asks for guidance. The results are negative for BRCA1 and BRCA2, but she has a positive family history for breast cancer. What do you advise?

A quartet of current clinical trials involving first-in-class molecules and CRISPR gene editing show great promise. STELLAR investigates a fusion protein in PAH, CodeBreak 200 studies a first-in-class of KRAS inhibitor, EMERGENT-2 focuses on a new treatment for schizophrenia, and NCT04601051 studies a gene editing drug for one form of amyloidosis.

In this cross-sectional study of US adults hospitalized with COVID-19 during January 2022 to April 2022, hospitalization rates from COVID were 10.5 times higher in unvaccinated persons and 2.5 times higher in vaccinated persons with no booster dose, respectively, compared with those who had received a booster dose.

The colorful fentanyl, known as “rainbow fentanyl,” has been identified in 18 different states and has been found in a variety of forms, including pills, powder, and blocks that resemble sidewalk chalk, according to a press release from the agency. No particular color has been found to have a higher potency through testing. According to the DEA, every shade, shape, and size should be viewed as being exceedingly harmful.

85-year-old woman with Hx of stage 3 chronic kidney disease New onset dyspnea and intermittent mild fever Slight difficulty opening her mouth; no dental caries or cervical lymphadenopathy Elevated CRP Elevated BUN Follow the case as it develops.

57-year-old man, otherwise healthy 2 month history of recurrent abdominal pain with diarrhea A history of celiac disease that had been well controlled with a gluten-free diet 5-pound unintentional weight loss since the onset of symptoms Tissue IgA > 30x over nl What conditions would you consider in your evaluation?