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The New England Journal of Medicine
Risks for ischemic stroke, hemorrhagic stroke, MI, and pulmonary embolism were all lower for older patients receiving a bivalent vaccine booster versus the monovalent vaccine. The results “provide reassurance regarding the continued use of this bivalent vaccine.”
Cardiology April 11th 2023
Medgadget
Getting a handle on the biochemical processes that govern how food is broken down and used within the body can be a daunting task for many, and even for those who understand it, monitoring with technology isn’t always possible. This is where Levels come into play. An instant metabolic analysis just a few hours after eating is only the beginning of the Levels experience; the app focuses on four major blood glucose levers in a gamified experience: diet, exercise, stress, and sleep. Dr. Lauren Kelley-Chew, Levels’ Head of Clinical Product, discusses all of this and more.
Cardiology April 5th 2023
ACP Internist
In a study of nearly 100,000 individuals aged 30 to 95 without any prior evidence of CVD, decline in peak metabolic equivalent of task score (METS) of greater than 1.0 was inversely proportionate to changes in mortality risk. METS were determined using symptom-limited exercise treadmill tests.
In this study, 800 patients admitted to ICU for severe CAP were andomized to 200mg IV hydrocortisone daily for 4 to 8 days or to placebo. By day 28, mortality rate was 6.2% versus 11.9% for the steroid and placebo groups, respectively. Rates for intubation and vasopressors were both approximately 40% lower in the test group as well.
Emergency Medicine April 5th 2023
Annals of Internal Medicine
Twelve-hundred (1,200) patients admitted for 48 hours or more for COVID were randomized to 2.5mg of apixaban or placebo twice daily for 30 days. The incidence of death or thromboembolism was low and similar in the two arms of this study. The study was terminated early and the authors say the results are imprecise.
Emergency Medicine March 29th 2023
Oncology News Central (ONC)
The study included 186 patients who had recently been diagnosed with advanced lung cancer (Stage IV). Investigators were curious about the relationship between depression levels and systemic inflammation ratio (SIR) biomarker levels at diagnosis. SIRs are made up of three biomarkers that are linked to inflammation in the body, which has been linked to lower survival rates. All participants also filled out a depression questionnaire. According to the findings, 35% of patients had moderate to severe depressive symptoms.
Oncology, Medical March 13th 2023