The Endocrine Society’s 2024 guidelines suggest against routine vitamin D screening and supplementation for most adults under 75, marking a significant shift in clinical practice recommendations.

The ABYSS trial questions the safety of interrupting long-term beta-blocker treatment in patients with a history of uncomplicated myocardial infarction, finding that discontinuation was not noninferior to continuation.

A prospective study involving over 170,000 participants from the UK Biobank found that moderate coffee consumption (3 drinks/day) was associated with a 48.1% lower risk of developing cardiometabolic multimorbidity compared to non-consumers.

The updated COVID-19 vaccines generate a more pronounced and specific immune response against current circulating strains, potentially reducing infection rates and, crucially, severe disease.

Greasy, high-fat foods can take up to 6 hours to digest, potentially disrupting sleep and exacerbating reflux symptoms when lying down.

The trial found no significant difference in hospitalization or death risk between patients using long-term oxygen therapy for 24 hours versus 15 hours per day, potentially offering more freedom for those with severe hypoxemia.