Articles related to Infectious Diseases

Working from the hypothesis that stomach ulcer bleeds in people on long-term low-dose aspirin therapy was secondary to H. pylori infection, this team gave antibiotic treatment to aspirin takers who test positive for the bacteria, and followed them for up to 7 years. Protection started rapidly and persisted, while diminishing somewhat, over the period of observation.

In a high-risk population, vaccination was better than prior infection, with incremental increase in protection with additional vaccination doses. Prior infection in unvaccinated individuals ranged from 16% to 49% vs omicron infection Versus unvaccinated, previously uninfected individuals, vaccine effectiveness at preventing omicron infection ranged from 19% to 83% with 2 doses and 41% to 88% with 3 doses Three vaccine doses offered significantly more protection than two doses, including among previously infected persons

Aniruddha Hazra, MD, of Howard Brown Health in Chicago, and colleagues found that of 90 people who tested positive for monkeypox following a single dose of Jynneos, 77% of the cases happened within 14 days of the first dose and 14% occurred within 14-28 days of the first dose. Five positive tests were returned following a second dose of the modified vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine in the eight cases that occurred 28 days after vaccine initiation.

A 5-year-old boy from China who had IgA vasculitis at age 2 presented with progressively painful skin ulcerations on his extremities for the past month. Find the reason behind the skin lesions on this young boy by answering the image challenge.

An observational analysis reviewed 54 studies and two medical record databases with data for 1.2 million individuals, to determine how many people experienced at least 1 of the 3 self-reported Long COVID symptom clusters 3 months after infection. The results indicate a Long COVID rate of 6.2%: 3.7% for ongoing respiratory problems, 3.2% for persistent fatigue with bodily pain or mood swings, and 2.2% for cognitive problems.

Reported neurologic complications of monkeypox include headaches and mood disturbances, and more rarely, encephalitis, transverse myelitis, and seizures. Historically neurologic complications of smallpox include encephalitis, transverse myelitis, and acute disseminated encephalomyelitis among others. Of concern is the possibility of viral persistence and systemic complications in immunocompromised individuals. Monkeypox should be considered when these neurologic symptoms are seen in high-risk populations.