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Cleveland Clinic Journal of Medicine
To sum up the reasons you should use caution: Quetiapine has a variety of effects, including sedation, influencing a number of central nervous system receptors. Quetiapine should only be used to treat insomnia in patients who also have co-occurring mood or schizophrenia spectrum disorders. Quetiapine is less frequently linked to extrapyramidal side effects and dystonia than many other antipsychotic medications, but it is more frequently linked to weight gain, metabolic syndrome, and QTc prolongation. Prior to beginning treatment and then on a frequent basis thereafter, measurements of body mass index, weight, blood pressure, fasting glucose, and lipid levels should be made, even at modest doses. Despite not producing euphoria, quetiapine is frequently misused to amplify or lessen the negative effects of illegal substances. For older patients, quetiapine has additional dangers.
Family Medicine/General Practice January 10th 2023
Journal of Neurology, Neurosurgery & Psychiatry
Leukodystrophies, deficiency-related metabolic diseases, genetic and acquired toxic/metabolic causes, and mitochondrial diseases were identified as the genetic and metabolic disorders of adulthood producing spinal cord signal changes. A number of adult metabolic and genetic illnesses that cause spinal cord atrophy without signal changes have also been discovered. The classification based on spinal MRI results is also offered, along with suggestions for the diagnostic process and alternative diagnoses.
Neurology January 10th 2023
Mayo Clinic Labs
It wasn’t carpal tunnel. It wasn’t just anxiety, and Ed wasn’t having a stroke. Even after a complete neurological assessment, it wasn’t “mild cognitive impairment.” For months, Ed’s life was plagued with psychiatric and movement disorders that puzzled his wife and his physicians. Read the narrative about how Ed was finally diagnosed, what happened next, and where he is now.
The American Journal of Psychiatry
The American Journal of Psychiatry presents this review of the most compelling articles that were covered in 2022: The Molecular and Cellular Alterations That Underpin Psychiatric Illnesses Shared and Distinct Neurobiological Mechanisms of PTSD Cognitive Deficits in Long-Term Cannabis Users Longitudinal Outcomes of Duration of Untreated Psychosis Accelerating TMS in the Treatment of Depression Infant Brain Development, Fragile X Syndrome, and Autism Spectrum Disorder Combining Computational Modeling and Postmortem Human Brain Studies to Uncover Synaptic Variability Contributions to Cortical Gamma Oscillation From the AJP Residents’ Journal: Identity and Stigma
Psychiatry January 10th 2023
MedPage Today
A poll conducted in 2021 shed light on the terrible state of many nurses’ mental health, and this story may be a reflection of those thoughts. When more than 9,500 critical care nurses were polled last October, more than half of them admitted to being “not emotionally well,” a trend that was most pronounced among younger nurses between the ages of 25 and 34 (Michael Odell was 27 years old at the time of his death).
Hospitalist January 10th 2023
Psychiatrist.com
High functioning depression is an oversimplified label for someone who effectively hides their persistent depression and seems to be managing their life well. The proper diagnosis is probably dysthymia. Dysthymia is difficult to detect until it intensifies into a major depressive episode. Asking questions about mood, sleep, medication and duration of depressive symptoms can help the clinician achieve a proper diagnosis.