Articles related to HEART FAILURE (HF)

“CHIP, especially non-DNMT3A CHIP, was independently associated with incident HF. Future research should explore the gene-specific mechanisms by which CHIP variants promote HF in humans.” — Study Authors, JAMA Cardiology

“Patients hospitalized for HFrEF in US clinical practice are at very high risk of poor clinical outcomes, even when prescribed quadruple medical therapy.” — Dr. Stephen J. Greene, Duke Clinical Research Institute

Continued collaboration across disciplines, enhanced focus on standardization, and investments in emerging technologies are imperative for bridging the gaps and driving innovation.

Beta-blocker use was not associated with reductions in all-cause mortality or cardiovascular mortality compared with the absence of beta-blocker therapy.

Loss of PRDM16 in adipocytes leads to increased sensitivity to ANGII and vascular fibrosis resulting in elevated blood pressure.

Melatonin supplements are widely thought of as a safe and ‘natural’ option to support better sleep, so it was striking to see such consistent and significant increases in serious health outcomes, even after balancing for many other risk factors.